15 Mai The brand new boundaries of one’s gene try expressed
Early studies for the Drosophila foreshadowing so it shopping for (Oliver, 1940) triggered this new demo of the Pontecorvo with his associates (Roper, 1950; Pontecorvo, 1952; Pritchard, 1955) one to a beneficial linear linkage chart would-be attracted to share the newest shipment out of mutant internet sites within just one gene from Aspergillus nidulans. This trying to find was soon followed closely by the fresh new unambiguous demo from the Benzer (1955) of a linear array of 8 sites, later on risen up to 308 (Benzer, 1961) throughout the registered nurse gene from phage T4, resulting in new postulated communications anywhere between a particular linear DNA molecule and the linkage chart away from a great gene, and eventually so you're able to presentations of one's co-linearity of the linkage chart together with polypeptide gene tool (Sarabhai, Stretton, Brenner and you will Bolle, 1964; Yanofsky mais aussi al., 1964).